解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::LIGHT and herpes virus entry mediator (HVEM) comprise a ligand-receptor pair in the tumor necrosis factor superfamily. These molecules play an important role in regulating immunity, particularly in the intestinal mucosa. LIGHT also binds the lymphotoxin beta receptor, and HVEM can act as a ligand for immunoglobulin fa...
journal_title:Seminars in immunopathology
pub_type: 杂志文章,评审
doi:10.1007/s00281-009-0157-4
更新日期:2009-07-01 00:00:00
abstract::The nicotinamide adenine dinucleotide phosphate (NADPH) oxidase of phagocytes is a multi-component electron transferase that uses cytoplasmic NADPH to convert molecular oxygen to superoxide anion, consequently delivering reactive oxygen species to the site of invading microorganisms. Together with soluble factors and ...
journal_title:Seminars in immunopathology
pub_type: 杂志文章,评审
doi:10.1007/s00281-008-0117-4
更新日期:2008-07-01 00:00:00
abstract::Systemic sclerosis (SSc, scleroderma) is a devastating, immune-mediated, multisystem disorder characterized by microvasculature damage, circulating autoantibodies, and fibroblast activation, leading to massive fibrosis of skin, vessels, muscles, and visceral organs. Scleroderma causes disability and death as the resul...
journal_title:Seminars in immunopathology
pub_type: 杂志文章,评审
doi:10.1007/s00281-008-0125-4
更新日期:2008-07-01 00:00:00
abstract::The intestine is normally colonized by a large and diverse commensal microbiota and is occasionally exposed to a variety of potential pathogens. In recent years, there has been substantial progress made in identifying molecular mechanisms that normally serve to protect the intestine from such enteric bacteria and whic...
journal_title:Seminars in immunopathology
pub_type: 杂志文章,评审
doi:10.1007/s00281-007-0100-5
更新日期:2008-02-01 00:00:00
abstract::The defining hallmark of IgA nephropathy (IgAN) is deposition of polymeric IgA1 in the glomerular mesangium accompanied by a mesangial proliferative glomerulonephritis. The mechanisms involved in mesangial polymeric IgA1 deposition and the initiation of inflammatory glomerular injury remain unclear. This lack of a com...
journal_title:Seminars in immunopathology
pub_type: 杂志文章,评审
doi:10.1007/s00281-007-0089-9
更新日期:2007-11-01 00:00:00
abstract::Human pregnancy is a metabolic and immune challenge for the mother who has to accommodate in her womb a semi-allogeneic fetus whose energy needs increase tremendously with gestation. Recent compelling research has suggested that proper inflammatory changes and oxidative balance are a requisite for successful pregnancy...
journal_title:Seminars in immunopathology
pub_type: 杂志文章,评审
doi:10.1007/s00281-007-0071-6
更新日期:2007-06-01 00:00:00
abstract::Since life in a terrestrial environment threatens mammals continuously with desiccation, the structural, cellular, biochemical, and regulatory mechanisms that sustain permeability barrier homeostasis have justifiably comprised a major thrust of prior and recent research on epidermal barrier function. Yet, the epidermi...
journal_title:Seminars in immunopathology
pub_type: 杂志文章,评审
doi:10.1007/s00281-007-0060-9
更新日期:2007-04-01 00:00:00